Symposium and business meeting: EAHP Istanbul. 17-22 October.
“Small B-cell lymphoid neoplasms in bone marrow: diagnostic advances.”
Workshop: Diagnostic difficulties in CLL, Bone marrow manifestations of LPL, MZL,SRPL, HCL-v and HCL, Small B-cell lymphomas in bone marrow multiclonality and composite lymphomas
26th ECP, London, 30 August – 3 September
Organiser: Jon van der Walt
2 sessions, a short course: “Haematopathology: Myeloproliferative Syndromes/MDS and Myeloproliferative Neoplasms: Mimics, progressions and transformation” and a Joint Short Course - Infectious Diseases Pathology / European Bone Marrow Working Group: “Infectious diseases involve the bone marrow”.
Symposium and business meeting: EAHP Uppsala. 25-30 September
“From molecular and histopathological bone marrow studies to therapy. Plasma cell myeloma and other plasma cell neoplasms - exciting new facts about an old disease. Blasts in the bone marrow: Myeloproliferative neoplasms. Recent advances in pathogenesis. Myelodysplastic syndrome: from bone marrow studies to new therapies. Impact of new prognostic markers on treatment decisions in acute myeloid leukaemia
Workshop: Unusual acute leukemias, Transformation of MPN and MDS, Myelosarcomas and other cases.”
Symposium and business meeting: EAHP Bordeaux. 20-25 September
“New WHO classification of myeloid neoplasms. Interactions between stroma and haematopoiesis in the bone marrow (niche, angiogenesis, fibrosis). MDS 5q-. Workshop: MDS and reactive mimickers of neoplasm”
Local Organsiser: Christine Beham-Schmid, Peter Regitnig, Ariane Aigelsreiter, Karin Lichtenegger
Evaluation of bone marrow biopsy. Normal bone marrow from birth to old age. Infectious disorders and effects of chemo/radiotherapy. Non-neoplastic haematological disorders (ITP, Perniciosa, polyglobulia). Acute leukaemias. Reactive states mimicking AML and MDS. Mast cell and histiocytic disorders.
WHO classification. MDS. Genetic predisposition to therapy related MDS and AML. Flow diagnostics of AML. CMMoL. Acute Panmyelosis. Treatment effects in MPN. Methods of JAK2 detection. Gene expression profiles in lymphoma subtyping. Viral infections in the BM. Post transplant biopsies. Infiltration patterns of lymphoma in the BM. Lymphoma with secretory capacity. Multiple myeloma and rare variants. Hodgkin’s lymphoma in the BM. T-cell leukaemias. Reactive and neoplastic B-cell infiltrates. Bone disorders. Metastasis.”
Scientific and business meeting: Athens. 6 October.
Organiser: Demi Anagnostou
Bone Marrow Pathology Short Course during ESP meeting in Istanbul. 8-13 September
First symposium and business meeting jointly with EAHP. Thessaloniki. 26 September – 1 October
Local organizer: Vasiliki Kaloutsi
“B-NHL involving primarily the bone marrow (including one lecture from Stein on “B-cell neoplasms with prominent plasma cell differentiation: overlaps and distinction”. T-NHL and T-cell dysfunction with primary manifestation in bone marrow and spleen. Recent advances in bone marrow diagnostics
Workshop subjects were related to the first two main subjects”
5th Course and business meeting. Palermo. 3-6 November
Local organizer: G Campesi, A M Florena, V Franco, E Maresi, E Orlando, L Russo, C Tripodo
“5th international Course on Bone Marrow Pathology”. Bone Marrow Biopsy: Processing and evaluation.Myrlodysplasia .Lymphoproliferative disorders. Myeloproliferative disorders. Challenging differential diagnosis; Disclosing new features; Iatrogenic and Post-transplant bone marrow changes
4th Course and business meeting. Athens. 19-23 May 1999
Local organizer: Demi Anagnostou
“Retrospective survey of development and application of bone marrow biopsies. Mechanisms of normal and dysregulated haematopoiesis. Update on methods for processing bone marrow biopsies. The art of bone marrow diagnosis. Application and Interpretation of immunohistochemistry on bone marrow biopsies. Clinical aspects of multiple myeloma. Plasma cell Dyscrasias on bone marrow biopsies. Bone and marrow changes under biphosphonates in benign and malignant disorders. Histiocytic disorders on bone marrow biopsies. Clinical aspects in MDS as reflexion of defective or dysregulated haematopoiesis. Myelodysplastic features on bone marrow biopsy: benign and malignant conditions. Diagnosis and prognosis of myelodysplastic syndromes. Apoptosis on bone marrow biopsies in MDS. Histological classification and staging of CMPDs correlated to cytogenetic findings. Atypical bone marrow biopsy findings in CMPDs and MDS. Pediatric MDS.”
2nd Course and business meeting. Basel. 15-18 November
Local organizer: Nina Hurwitz
The bone marrow: from patient to report. Taking a biopsy. Immunohistochemistry. Reporting the bone marrow. The classification and clinical aspects of MDS. The bone marrow biopsy and bone marrow smear in MDS. Myelodysplastic syndromes not included in the FAB-classification. Differential diagnosis of the hypoplastic bone marrow. Iatrogenic MDS and reactive dyshaematopoiesis. Round table discussion on MDS. Update in childhood preleukaemic disorders. Histopathology of CML and its differential diagnosis. Polycythemia vera and thrombocytopenia. Myelofibrosis. Myelodysplastic syndromes versus chronic myeloproliferative diseases. AML and its differential diagnosis. Bone marrow changes post chemotherapy and/or post transplantation. Round table discussion on MPD. New trends in hematopoietic precursor cell transplants. The pathology of plasma cell dyscrasia. Bone marrow involvement in large cells lymphomas. Bone marrow involvement by Hodgkin's disease and its differential diagnosis. Non-neoplastic infiltrates in the bone marrow. Bone diseases in core biopsies of the bone marrow. Round table discussion on lymphoproliferative disorders.
1st Course and business meeting. Utrecht. 11-14 may
Organiser: Jan van den Tweel
”Bone marrow development and interpretation. Technical aspects of bone marrow investigation. Bone marrow stroma; its role in haematopoiesis. Clinicopathological features of myelodysplastic syndromes. Histological characteristics of MDS. MDS-like diseases, with particular emphasis on HIV-associated dysplasia. Bone marrow biopsy in aplastic anaemia. Hypoplastic MDS/AML versus aplastic anaemia. Influence of haematopoietic growth. FAB-classification and clinical aspects of leukaemia. Bone marrow features in acute leukemia. Effect of leukaemia therapy on bone marrow histology. Detection of minimal disease. Differential diagnosis of chronic myeloproliferative disorders. Evolution of chronic myeloproliferative disorders. Bone marrow fibrosis and its patterns. Myelodysplastic syndromes versus chronic myeloproliferative disorders. Acute leukaemia and transient myeloproliferative disorder in Down syndrome. Bone marrow involvement by B-cell lymphomas. Bone marrow involvement by T-cell malignant lymphomas. Reactive lymphoid aggregates in the bone marrow. Potential of bone marrow biopsy/aspirate for classification, staging and monitoring of multiple myeloma. Bone marrow involvement in plasma cell dyscrasias. A clinician’s view. Adhesion molecules in the pathophysiology of multiple myeloma.”
EAHP meeting in Bologna, September 21-25. Further discussions were held in Athens in December 1992
The Bone Marrow Study Group was conceived initially from an idea that emerged during a discussion between Demi Anagnostou and Jan van den Tweel, with the aim of exchanging views on bone marrow diagnostic problems and advances with others interested in the field.
An invitation letter, signed by Demi Anagnostou and Jan van den Tweel in Athens in January 1993 was addressed to Kristin Henry, Konrad Muller-Hemerlink, Nina Hurwitz, Jacques Diebold, Bertha Frisch and Stephano Pileri, who formed the first core of the Group.
The Group acquired official status for the first time during the business meeting in Basel , 2001, with election of a committee and president (Vito Franco, Hans Kreipe, Demi Anagnostou)